Issues/Health Hazards

Transcriptome profiling reveals bisphenol A alternatives activate estrogen receptor alpha in human breast cancer cells by Robin Mesnage et al, BioRXiv, March 2, 2017
BPA alternatives are not necessarily less estrogenic in a human 23 breast cancer cell model. Three bisphenols (BPAF, BPB, and BPZ) were more estrogenic 24 than BPA. The relevance of human exposure to BPA alternatives in hormone-dependent 25 breast cancer risk should be investigated.

Bisphenol A Exposure in Children With Autism Spectrum Disorders 
by Stein et al, Autism Research., June 8, 2015
This research study focused on the plasticizer, Bisphenol-A (BPA), exploring it’s possible link to autism spectrum disorders (ASD). Genetic and environmental components have been suspected of involvement with ASD.  To determine whether there was a relationship between BPA exposure and ASD, urine specimens were collected from 46 children with ASD and 52 controls, utilizing the major pathway for BPA metabolism and excretion - glucuronidation. The results suggest there is an association between BPA and ASD.

Plastic chemical BPS damages egg cells 
by Brooks Hays, Science News, Aug. 9, 2016
In response to growing concerns about the chemical BPA, many plastics producers began using a substitute called BPS.  New research suggests the chemical may be just as harmful.


Public Health Statement for Styrene - Toxic Substances Portal - Styrene,  June 2012
This Public Health Statement is the summary chapter from the Toxicological Profile for styrene. It is one in a series of Public Health Statements about hazardous substances and their health effects. A shorter version, ToxFAQsTM, is also available. This information is important because this substance may harm you. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present.

Big Chem, Big Harm?
New York Times – by Nicholas Kristof, Aug. 25, 2012
Like a lot of Americans, Kristof used to be skeptical of risks from chemicals like endocrine disruptors that are all around us. What could be safer than canned food? He figured opposition came from tree-hugging Luddites prone to conspiracy theories.
Yet, a few years ago, he began to read the peer-reviewed journal articles, and it became obvious that the opposition to endocrine disruptors is led by serious scientists, yet they don’t often have the ear of politicians or journalists.  But Big Chem does and following the script of Big Tobacco a generation ago, so far, they have blocked any serious regulation of these endocrine disruptors.

Plastics Linked to Heart Disease
 Scientific American by David Biello  January 13, 2010
Higher concentrations of bisphenol A—a common ingredient in plastics found in products ranging from polyester to water bottles—have been linked to heart disease, according to a new follow-up study. A similar study was performed by the same team in 2008 using older data from a survey conducted by the U.S. Centers for Disease Control and Prevention (CDC).  A second study links BPA measured in human urine to a higher risk of cardiovascular disease

Polluted Pets
- High Levels of Toxic Industrial Chemicals Contaminate Cats And Dogs - EWG, April 17, 2008
In the first study of its kind, Environmental Working Group found that American pets are polluted with even higher levels of many of the same synthetic industrial chemicals that researchers have recently found in people, including newborns.

The results show that America’s pets are serving as involuntary sentinels of the widespread chemical contamination that scientists increasingly link to a growing array of health problems across a wide range of animals—wild, domesticated and human.

Just as children ingest pollutants in tap water, play on lawns with pesticide residues, or breathe in an array of indoor air contaminants, so do their pets. But with their compressed lifespans, developing and aging seven or more times faster than children, pets also develop health problems from exposures much more rapidly. The National Research Council has found that sickness and disease in pets can inform our understanding of our own health risks (NRC 1991). And for anyone who has lost a pet to cancer or another disease potentially linked to chemical exposures, this sentinel role played by pets becomes a devastating personal loss.